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io9 has put together a handy list of 25 rules of Comic-Con etiquette that you're advised to follow if you go to the convention.

Here are some examples:

10.) If you're over 18, don't ask panelists if they're single.
11.) If you're between 8 and 17, you're allowed to inquire about panelists' relationship statuses, but be prepared for a chorus of nervous titters.
16.) If you want to take a photo of a cosplayer, it's proper form to ask first. Most will be happy to oblige and pose fiercely.

Do you have any other ideas for rules that a Comic-Con goer should follow? If so, leave them in the comments!

Source: io9